The Bulletín of Kanagawa Dental College

Vol. 36 No. 2       September- 2008

ISSN: 0385-1443      UBIC: 65

ABSTRACT

Titanium dioxide (TiO2) photocatalyst coated with fluoridated apatite (FAp-TiO2) was synthesized by adding a fluoride ion to TiO2 coated with apatite (HAp-TiO2). This study investigated the antifungal and inhibitory effects of acrylic resin containing FAp-TiO 2 against Candida albicans. The specimens were randomly divided into 4 groups (n=4) as follows: 1) acrylic resin (control); 2) acrylic resin containing 5% FAp-TiO2 (FAp); 3) acrylic resin containing 5% HAp-TiO2 (HAp); 4) acrylic resin containing 5% TiO2 (Ti). For the assay, C. albicans cells were placed onto the specimens under UVA from a black light source.In both the antifungal activity and ínhibitory tests, there was a statistically significant decrease was observed with FAp, HAp, and Ti when compared with the control (p<0.01). Scanning electron microscope observations revealed dents and irregular contours in C. albicans in the FAp group. The results suggest that acrylic resin containing FAp-TiO2 has a strong antifungal effect and prevents the adhesion of C. albicans. Key words: Titanium dioxide photocatalyst / Fluoridated Apatite /Antifungal effect /Acrylic resin.

| Volver |