The Bulletín of Kanagawa Dental College

Vol. 37 No. 1       MARCH- 2009

ISSN: 0385-1443      UBIC: 65

ABSTRACT

The Grimelius silver method can be used to stain the secretory granules of various endo crine cells. The present study investigated neuroendocrine granules of the human submandibular gland (HSG) by the Grimelius silver method using paraffin sections. Argyrophilic Grimelius silver positive-cells were mainly observed among the serous cells of HSG. HSG may produce granules with neuroendocrine-like features. Key words: Grimelius silver method / Argyrophilia / Human submandibular gland.

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