JAPANESE JOURNAL OF ORAL & MAXILLOFACIAL SURGERY

Vol. 54 No. 10       2008

ISSN: 0021-5163      UBIC: 151-J

ABSTRACT

Acanthosis nigricans (AN) is an uncommon dermatosis with systemic brownish hyperpigmentation, velvety thickening of the skin, and verruca-like papules on the oral mucosa. It was classified into benign, pseudo, and malignant types by Curth in 1952. Generally, the benign and pseudo types are associated with endocrinopathies and obesity. The symptoms of these types are not as severe as those of malignant type. Malignant type is related to visceral malignant tumors. In addition, malignant type is frequently associated with oral mucous lesions. Although oral lesions have been reported in 25 % to 50 % of all AN cases, only a few articles have reported oral lesions associated with AN in the oral and maxillofacial region. In this report, we describe a case of AN with oral pallipomatous lesions without a visceral malignant tumor. Keywords: acanthosis nigricans, papilloma, papillomatosis.

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