JAPANESE JOURNAL OF ORAL & MAXILLOFACIAL SURGERY

Vol. 54 No. 3       2008

ISSN: 0021-5163      UBIC: 151-J

ABSTRACT

We report a case of glandular odontogenic cyst (GOC) arising in the mandible. The patient was a 55- year-old woman who presented with a painful swelling of the right premolar region of the mandible. Roentgenographic examination revealed a multilocular radiolucent lesion from the right first molar across the midline to the left second premolar region. The clinical diagnosis was a mandibular cyst. Enucleation of the cyst and extraction of the teeth were performed with the patient under general anesthesia. Histological examination showed a multicystic lesion partially lined by non-keratinized epithelium with focal plaque-like thickening. The surface epithelium included eosinophilic cuboidal and ciliated cells. Cyst-like spaces and glandular structures were also observed within the epithelium. Epithelial islands were also seen in conoective tissue of the cyst. Immunohistochemically, epithelial cells were strongly positive for cytokeratin (CK) 13 and 19, but almost negative for CR18. The histological diagnosis was GOC. The postoperative course was satisfactory, and no recurrence has been noted 4 years 6 months after the operation. Key words: glandular odontogenic cyst, mandible

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